Prazosin inhibits small intestinal transit in the rat
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چکیده
منابع مشابه
The Relationship among Glycemic, Small Intestinal Transit and Insulinemic States in Normal Mice
Gastrointestinal (GI) complications during diabetes mellitus (DM) are common. Attempts to ascribe changes in the glycemic state to the altered GI (gastrointestinal) motility in experimental models yielded varied results. In the present study the possible cause-effect relationship between the changes in the glycemic, insulinemic states and small intestinal transit (SIT) in normal mice was examin...
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The time of breath hydrogen appearance (T) after oral lactulose was determined in 98 patients in London who had been to the tropics. Fifty-six controls from three different ethnic groups had no evidence of gastrointestinal disease; 23 had tropical malabsorption, which was severe in 10; and 19 had chronic diarrhoea without malabsorption. Mean T was significantly delayed in patients with tropical...
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Introduction: Artemisia dracunculus L. belongs to Asteraceae family, and is a medicinal plant widely used in traditional medicine as a remedy for gastrointestinal disturbances. This study was undertaken to evaluate the effects of essential oil of A. dracunculus (EOAD) on the rat alimentary tract. Methods: The EOAD was extracted by Clevenger apparatus using hydrodistillation. LD50 was calcula...
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The effects of morphine treatment on small intestinal propulsion and contractile activity were investigated in unanesthetized rats. Intragastrically, s.c. and i.c.v. administered morphine produced dose-related decreases in the transit of a radioactive marker (51Cr) through the small intestine. Morphine was most potent after i.c.v. administration whereas the intragastric route was the least pote...
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A lactulose hydrogen breath test was performed on 10 patients with cystic fibrosis and 15 control subjects matched for age and sex. All normal subjects had a fasting breath hydrogen concentration of less than 20 ppm. In contrast, seven of the patients with cystic fibrosis had high concentrations (25-170 ppm), which fell to 20 ppm or below on prolonged fasting (14-23 hours). Two patients showed ...
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ژورنال
عنوان ژورنال: British Journal of Pharmacology
سال: 1984
ISSN: 0007-1188
DOI: 10.1111/j.1476-5381.1984.tb10792.x